Massachusetts General Hospital — Est. 2014

Great ideas to improve healthcare are everywhere.

We turn frontline clinical pain points into deployed, validated care — from the hospital to the home.

THE RECORD

Proof, not promises.

50+

projects taken from idea to implementation

80K+

clinicians reached by HTL-built tools

200

countries using our clinical apps

10+

years turning ideas into care

FEATURED WORK

A decade of deployed innovation.

Acute Care at Home

Acute Care at Home

Meeting patients where they are — delivering hospital-level acute care in the comfort of a patient’s own home.

Active

Clinical Decision Support

Clinical Decision Support

Putting evidence-based guidance directly in clinicians' hands — building and validating the digital tools that support critical decisions at the point of care.

Active

Open Innovation

Open Innovation Contests

Turning the daily frustrations of MGH's front-line staff into tested solutions, through an open-innovation program run with Harvard Business School.

Active

WHERE DO YOU COME IN?

Find your path.

STARTUPS · HEALTH-TECH · MGH CLINICIANS

Collaborate

Bring us a pain point or a technology. We co-develop, validate, and help implement it in real clinical settings.

RESIDENTS & RESEARCHERS

Fellowship

Spend a year building real care-delivery projects on the front lines through our Applied Research Fellowship.

PARTNERS · FUNDERS · THE CURIOUS

Our Work

See the full record — active and archived — of what the lab has designed and deployed since 2014.

OUR APPROACH

We start where the work is hard.

Every project begins with a frontline pain point. We pair clinicians, engineers, and entrepreneurs to design, validate, and implement solutions that last — carrying forward the same spirit of invention that created the famous Ether Dome.

HTL

Healthcare Transformation Lab at

Massachusetts General Hospital

© 2026 Healthcare Transformation Lab

Mass General Brigham