The Healthcare Transformation Lab at Mass General was created to improve the experience and value of healthcare by inspiring collaborative innovation and leveraging novel technologies.
Founder & Director
Eric Isselbacher, MD, MHCDS
Eric Isselbacher is the Founder & Director of the Healthcare Transformation Lab. He is a graduate of Harvard College and Harvard Medical School. He completed both his medical residency and cardiology fellowship at Massachusetts General Hospital. In 1996 he joined the staff of the Cardiology Division at Mass General. Dr. Isselbacher is an Associate Professor of Medicine at Harvard Medical School. He is motivated to innovate by the fact that healthcare providers today are stretched to the limit, if we hope to improve the efficiency, quality, and experience of healthcare, it can’t be by working harder or faster. It will have to be by a willingness to break with tradition and embrace the science of innovation.
Paula McCree is Managing Director of the Healthcare Transformation Lab. Motivated by her desire to be part of a team that creates innovative solutions in healthcare that work, she brings her passion and interests to settings where she can facilitate the process through which innovation in healthcare can have an impact on how services are delivered and received. Her experience in a variety of healthcare settings developing new products and designing new programs gives her a unique perspective and understanding of innovation in the healthcare delivery system. Paula holds a BS in Biological Anthropology from Harvard and an MS in Nutrition from Tufts. Influenced by her training as a yoga instructor and stress management and resiliency program facilitator, she brings a mindful perspective to organizational development and creates purpose driven work environments where people bring their best selves and innovation flourishes.
Jared Conley, MD, PhD, MPH
Dr. Jared Conley is an emergency physician at Massachusetts General Hospital and Harvard Medical School. He serves as the Associate Director of the MGH Healthcare Transformation Lab, where he leads a team of clinicians and engineers to enhance the quality and affordability of acute healthcare through technology and innovation. He additionally serves on the leadership team for MGH’s Home Hospital program. His work explores the relationship between acute health needs and the optimal setting and provision of care—and the enabling opportunity for digital health to improve the quality, safety, and cost of care. His work has been featured in various medical journals, including NEJM Catalyst, JAMA Internal Medicine, and Stroke. He completed a joint MD/PhD program at Case Western School of Medicine, as well as received an MPH from The Dartmouth Institute. His clinical training was obtained at Harvard (MGH/BWH) and he completed a fellowship in healthcare delivery innovation at Stanford University.
Cardiologist, Clinical Affiliate
Aaron Aguirre, MD, PHD
Aaron Aguirre is a cardiologist and critical care specialist at the Massachusetts General Hospital and Harvard Medical School a clinical affiliate of the Healthcare Transformation Lab. He received his medical degree from Harvard Medical School and his doctoral degree in electrical and biomedical engineering from the Massachusetts Institute of Technology. He trained in internal medicine, cardiology, and critical care at the Brigham and Women’s Hospital. Dr. Aguirre’s graduate work focused on the development of high-resolution optical imaging methods and catheter technologies for clinical applications, and he has significant experience in the creation and preclinical validation of novel medical devices. His current research at the MGH Center for Systems Biology utilizes innovative molecular imaging and microscopy techniques to investigate the biology of myocardial infarction (heart attack) and related forms of heart disease.
Jennifer Mann is an Innovation Manager with the Healthcare Transformation Lab. Jennifer holds dual Bachelor of Science degrees in Biomedical Engineering and Mechanical Engineering from Worcester Polytechnic Institute. She also holds a Master of Engineering degree in Biomedical Engineering from Boston University. During her graduate program, Jennifer developed a keen interest in medical device product development and innovation management strategies. Since graduating, she has devoted the focus of her career to bringing innovative healthcare technologies to market and into the hands of patients and caregivers. Prior to joining the Healthcare Transformation Lab, Jennifer worked at a boutique technology consulting firm where she counseled med-tech companies on new product development, innovation strategy, and IP portfolio management.
Halim Chu is a fullstack software engineer with the Healthcare Transformation Lab. She enjoys building web-based and mobile apps that improve the delivery of care to high-risk patient populations, with a particular interest in mental health conditions. After several years of studying code on her own, she attended the Grace Hopper program within Fullstack Academy of Code in New York City. During her time at Grace Hopper, she was part of a team that built a web-based app that tracks and predicts the user’s mood using machine learning. She graduated from University of California, San Diego with a BA in Psychology.
Fellow in Healthcare Innovation
Michael J. Senter-Zapata, MD
Mike Senter-Zapata is a Staff Hospitalist at Brigham and Women’s Hospital and Harvard Medical School. His research interests include studying clinical decision support tools and point-of-care healthcare mobile apps, particularly around advanced cardiac life support (ACLS) and basic life support (BLS) resuscitation. During residency, Mike recruited a diverse team of fellow co-residents, Harvard Medical School students, and faculty across Internal Medicine, Cardiology, and Emergency Medicine disciplines to develop a novel iOS mobile app that trains residents in leading effective hospital codes. He received research grants from the Brigham Education Institute (BEI), the Internal Medicine Residency Program Office, and the Mass General Brigham Office of Graduate Medical Education Center of Expertise (COE) in MedEd to study its efficacy. He is continuing this research as an MGH HTL Innovation Fellow by conducting a randomized control trial in the BWH STRATUS Center for Medical Simulation to further assess the role of mobile technology as a tool for improving resident education and patient bedside care delivery. Outside of the hospital, Mike enjoys traveling with his wife, Tasha (current PGY-4 Psychiatry Resident at MGH), hiking national parks, playing the guitar, and photography. He completed his undergraduate education at Harvard University, medical school at Washington University School of Medicine in St. Louis, and Internal Medicine residency training at Brigham and Women’s Hospital.
Hospitalist, Clinical Affiliate
Jocelyn Carter, MD, MPH
2017-2018 Aetna Foundation Fellow in Healthcare Innovation
Jocelyn Carter, MD, MPH is a 2017 Aetna Foundation Fellow in Healthcare Innovation with the Healthcare Transformation Lab. Clinically prepared in preventive medicine, internal medicine and leadership at Dartmouth Hitchcock Medical Center, Dr. Carter is passionate about experiential learning, scalable and cost-efficient initiatives, outcomes research, and healthcare information technology driving the redesign of patient-centered care in healthcare innovation. She is an active member across the MGH community, serving as the MGH Center for Diversity and Inclusion Manager of Trainee Affairs, and on the Department of Medicine’s Albright Medicine Service and Internship Selection Committee in addition to being a practicing internal medicine hospitalist. A recent awardee of a 2017 Partners Healthcare Center for Population Health Delivery System Innovation Implementation Grant, Dr. Carter and her team are studying the impact of patient-community health worker pairings upon hospital discharge on health care outcomes in high risk populations. She is an editor of the Society of Hospital Medicine Clinical Quick Talks and is a regular reviewer for esteemed academic journals.
General Surgeon, Clinical Affiliate
Numa Perez, MD
Numa Perez, MD, is a 2018-2019 Aetna Foundation Fellow in Healthcare Innovation with the Healthcare Transformation Lab, and the 2018 Claude E. Welch Research Fellow in the Department of Surgery at Massachusetts General Hospital. Numa spent his childhood in El Salvador before coming to the United States and joining the U.S. Marine Corps where he worked as an Avionics Technician of the CH-53E Helicopter. From there, he moved onto college and worked as a Research Engineer at Lockheed Martin Aeronautics. This diverse background in technology and system design, combined with his Surgical training at MGH, have prepared him well to tackle issues that lay at the intersection between healthcare innovation, outcomes and disparities. Numa’s goal is to rethink and redesign the entirety of the perioperative patient experience, while leveraging technology to make it streamlined and more patient-centered, thus leading to improved patient satisfaction and postoperative outcomes. While hoping to enhance quality for all, Numa’s goal is to simultaneously bridge the disparity gap that affects so many patients at MGH and around the nation. Numa graduated with his BS in Electrical Engineering and Computer Sciences from the University of California, Berkeley, and went on to earn his medical degree at Harvard Medical School. Outside of work, Numa enjoys spending time with his wife Rachel, his daughter Olivia, and his son Numa III.
Cardiologist, Clinical Affiliate
Nicholas Houstis, MD, PhD
Nick Houstis is a 2020 Fellow of the Healthcare Transformation Lab as well as a cardiologist and scientist at Massachusetts General Hospital. With graduate training in computer science (MS, Purdue University) and biology (PhD, MIT) he has sought to apply computation to a spectrum of research questions, from the molecular mechanism of insulin resistance to the pathophysiology of exercise intolerance in heart failure. His current focus is on developing decision support tools to help physicians reason about complex physiology in the intensive care unit. Such tools could help tame this complexity, improving the quality of care as well as democratizing it.
Critical Care Physician, Clinical Affiliate
Amy Dickey, MD
Amy Dickey, MD is a Healthcare Transformation Lab Fellow in Healthcare Innovation and an instructor in the Pulmonary and Critical Care Division of the MGH Department of Medicine. She is passionate about adapting and applying technologies for use in porphyria, a family of rare genetic diseases affecting the production of heme. Her interest in porphyria arises from personal experience, as she personally has erythropoietic protoporphyria (EPP). This disease causes painful sensitivity to light but currently has no FDA-approved treatments. Her innovation project focuses on developing and applying technologies to provide quantitative endpoints for clinical trials in EPP. For this project, she was recently awarded a Spark Grant from the MGH Medicine Innovation Program. In addition to being an HTL fellow, she is also a Protect the Future Trainee of the American Porphyria Foundation, a program designed to train the next generation of porphyria specialists.
Emergency Physician, Clinical Affiliate
Andrew Chu, MD, MPH, MBA
Andrew “Andy” Chu, MD is a Fellow in Healthcare Innovation with the Healthcare Transformation Lab. He is passionate about transforming healthcare through the use of digital health solutions and care delivery, with special emphasis on developing technologies that improve the longitudinal care, patient-provider experience, and clinical outcomes of patients from high-risk, underserved communities. He is currently a resident physician in the Harvard Affiliated Emergency Medicine Residency (HAEMR) program at Massachusetts General Hospital and Brigham & Women’s Hospital. Andrew earned his MD at Boston University School of Medicine and his MPH at Harvard T.H. Chan School of Public Health. For his prior work in digital health and innovation, he is grateful to have received the American Medical Association Leadership, Massachusetts Medical Society Scholars, and the ECRI Health Devices Achievement Awards. Outside of work, Andrew loves to spend time with his wife, Halim, and dog, Birdie.
Olivia S. Jung, PhD
Olivia Jung is a research affiliate of the Healthcare Transformation Lab, as well as a faculty affiliate of the Laboratory of Innovation Science at Harvard University and an assistant professor in health policy and management at Emory University. Dr. Jung’s research in the field of health care management is informed by her interdisciplinary training in health policy, organizational behavior, and general management. Using mixed methods and organizational theories, Dr. Jung studies ways to motivate and organize frontline workers to innovate and engage in quality improvement work. Her research program is built around examining organizational structures, incentives, and cultures that support innovations—from generating ideas to implementing practices—that aim to improve health care delivery processes and outcomes. At HTL, she helped to design, implement, and study the first iteration of the Ether Dome Challenge in 2014. Dr. Jung holds a PhD and AM in Health Policy & Management from Harvard Business School at Harvard University, a BS in Economics from the Wharton School of Business and a BA in International Studies from the College of Arts and Sciences at the University of Pennsylvania.
Entrepreneur in Residence
Gregory Snyder, MD, MBA
Greg Snyder is a clinician and physician innovator applying technology to improve healthcare quality and experience. He is a graduate of Princeton University, Jefferson Medical College, Brigham & Women’s Hospital Internal Medicine residency and Harvard Business School. He practices hospital medicine at Newton-Wellesley Hospital, is affiliate faculty at Ariadne Labs, and is a clinical lead for Medically Home, which uses telemedicine and remote patient monitoring to provide hospital-level care to patients in their homes. Greg has partnered with diverse healthcare technology ventures to improve digital patient navigation (Medumo), virtual-first primary care (Dialogue), and AI-guided dermatology (LuminDx). He is now focused on bringing healthcare services to patients where they are most comfortable, in order to improve care quality and patient experience.
Rahul Prabhu is an engineer and part-time researcher at the Healthcare Transformation Lab. He graduated with a BS in Biomedical Engineering and a Computer Science minor from Georgia Tech and has worked as an R&D engineer at Boston Scientific since graduating in 2020. Rahul was drawn to HTL after noticing a need to improve healthcare access to underserved communities during the pandemic. By leveraging his engineering skills to understand how healthcare technology can be leveraged in home care settings, Rahul hopes to also gain an understanding of how social determinants of health can be addressed to bridge clinical gaps in the patient-physician experience.
At HTL, our enduring mission is to improve the experience and value of healthcare for patients and clinicians. We do this through collaborative innovation. We facilitate the creation and scale of transformative clinical care projects, train future leaders of healthcare innovation, and serve as a knowledge center for clinicians and our leadership about emerging technologies and best practices for integrating them into healthcare operations.
Knowledge Center for Emerging Technologies
Advances in digital health technology, combined with a focus on human-centered design, are creating the unique opportunity to re-imagine patient care to make it more continuous, coordinated, and convenient.
HTL serves as a central resource for all stakeholders in the healthcare delivery ecosystem to link front-line pain points with the best validated technology solutions that will change how healthcare is delivered and received.
Clinical Care Accelerator
We work directly with the front-line clinicians to understand real issues and pain points. We focus in areas such as remote patient monitoring, telemedicine, and patient engagement. As promising ideas that transform how healthcare is delivered and received emerge, HTL accelerates innovation by directly assisting in the creation, development, and validation of the ideas. Further, we champion their implementation to ensure a sustainable impact on patient care.
Training Future Leaders
HTL develops and enhances innovation skills for clinicians to improve their ability to have impact in transforming how care is delivered and received.
Our workshops, entrepreneur in residence rotations, and innovator training provide learning and mentoring opportunities for clinicians interested in technology innovation.
Our collaborations maximize impact.
We work with clinicians, administrators, general staff, students, designers, developers and industry – just to name a few. We bridge the gap between promising healthcare innovation startups and front-line clinical pain points in order to ensure the translation of ideas and prototypes into sustainable solutions. Whether the goal is to clinically validate technology or to test a new use case, we partner with industry, as well as start-ups, to study the impact of healthcare delivery interventions with our digital health innovation research expertise.
Our Collaborators include the following groups and organizations:
September | AHA Collaboration
The MGH Healthcare Transformation Lab launched the MGH PALS app. A collaboration with the American Heart Association (AHA) and MGH/Harvard Medical School, it is a free digital companion for use at the bedside performing Pediatric Advanced Life Support (PALS)
July | HTL Fellow Project
The CareSense Pilot run by Numa Perez, MD completed and launched as an operational program in the Department of Surgery
July | Ether Dome Challenge Year 5
The fifth Ether Dome Challenge launches with the Nursing and Patient Care Services, Center for Innovations in Care Delivery
October | HTL Project
The MGH ACLS app reached 20,000 users
December | HTL Project
The Eko (remote stethoscope) pilot with Home Hospital launched
May | AHA Collaboration
HTL announces its collaboration with the American Heart Association (AHA) to create MGH ACLS, an app that offers algorithms and key resources to clinicians responding to life-threatening cardiac emergencies
March | Personnel
Paula McCree joins as Managing Director overseeing strategy planning and implementation, general operations and administration, and special projects
March | HTL Project
HTL announced its collaboration with the American Heart Association (AHA) to create MGH ACLS an app that offers algorithms and key resources to clinicians responding to life-threatening cardiac emergencies
July | Applied Research Fellowship in Healthcare Innovation
The fourth Applied Research Fellow in Health Care Innovation, Nicholas Houstis, MD, PhD, joins the HTL team
July | Personnel
Greg Snyder, MD, joins HTL as Entrepreneur in Residence focussing on Home Hospital
September | HTL Project Launch
MGH ACLS App is launched internationally via the Apple Store
July | HTL Collaboration
HTL collaborates with MGH Home Hospital as technical advisor managing, introducing, and piloting new technology to facilitate all aspects of the program operations
May | New Collaboration
HTL consults and judges during Pulse@MassChallenge pitch and demo days and matches with two start-ups: Lighter and Signum
July | Applied Research Fellowship in Healthcare Innovation
The third Applied Research Fellows in Health Care Innovation, Amy Dickey, MD and Andy Chu, MD, join the team
July | Personnel
Jared Conley, MD, PhD, MPH, Emergency Physician joins as Associate Director and Technical Advisor for the Home Hospital Program
August | Personnel
Erik Reinertsen, MD, PhD, joins HTL as Innovator in Residence in Artificial Intelligence and Machine Learning
January | Mojo 3.0 is Launched
The result of our collaboration with LCS and MGPO, Mojo, a revolutionary paging system on a smartphone is released
July | Personnel Transition
Julia Jackson accepts a new role as Director, Digital Health with Sage Therapuetics
July | Applied Research Fellowship in Healthcare Innovation
The second Applied Research Fellows in Health Care Innovation, Numa Perez, MD and Kostantin Stojanovic, MD, join the team
August | Ether Dome Challenge Year 4
The fourth Ether Dome Challenge launches with the Department of Surgery
December | Personnel Transition
Maulik Majmudar accepts a new role as Chief Medical Officer with the Amazon Halo organization
July | MGH HTL Applied Research Fellowship in Healthcare Innovation
First Applied Research Fellows in Healthcare Innovation, Yanik Bababekov, MD and Jocelyn Carter, MD start their work with HTL
January | MassChallenge Collaboration
HTL consults and judges during Pulse@MassChallenge and matches with two start-ups, Medumo and Emerald
March | Ether Dome Challenge Year 3
The third Ether Dome Challenge launches with the Cancer Center
April | New Collaboration
HTL provides project support to the second Medicine Innovation Program grant recipient Areej Al-Jawahri to create the DreAMLand app
May | Co.Create Collaboration
HTL provides co-development support for three student start-ups: MobioSense, Pine Health, Rendever
December | MassChallenge Collaboration
HTL consults and judges during Pulse@MassChallenge and matches with four start-ups: Day Zero, Diagnostics, Astarte, and Dynamicare
March | mLab Collaboration
Collaboration between HTL, the Laboratory of Computer Science, the Mass General Physicians Organization, and Information Systems is formalized to form the mLab established to provide one-stop support to digital innovators across MGH
February | MassArt Collaboration
MassArt students conduct user experience research on wayfinding across MGH
February | Co.Create Collaboration
HTL provides co-development support for a student project: QuantaFit
April | Applied Research Fellowship in Healthcare Innovation
Applications open for the inaugural HTL Applied Research Fellowship in Healthcare Innovation Award
July | New Collaboration
HTL provides project support to the first Medicine Innovation Program grant recipient Kim Blumenthal, MD to create the Allergy Passport app
December | Novelline Innovation Speaker Series
Novelline Innovation Speaker Series bringing leaders in healthcare innovation, design-thinking, and care delivery to share their experiences and lessons learned with members of the MGH community is launched
March | New Collaboration
HTL partners with Department of Medicine Innovation Taskforce to award the first Collaborative Innovation Grant and on the PrOE PCI project launch
April | New Collaboration
HTL collaborates with MGPO Kitty Hawk Initiative to kick-off of Cardiology’s medical scribe pilot
May | HTL Clinical Affiliate Joins
Aaron Aguirre, MD, PhD, joins HTL as Clinical Affiliate in Cardiac Digital Health
June | Ether Dome Challenge Year 2
The second Ether Dome Challenge launches with the Department of Cardiology
December | Co.Create Collaboration
HTL provides co-development support for two student start-ups projects: Ask Wilhem and EarID
April | HTL Launch
Founded by Eric Isselbacher, MD, the MGH Healthcare Transformation Lab is launched with leadership team including Maulik Majmudar, MD, Associate Medical Director and Julia Jackson, Managing Director. Hal Gregersen, Executive Director of the MIT Sloan Leadership Center is Keynote speaker
July | Ether Dome Challenge
The Ether Dome Challenge Program with the Department of Cardiology launches in collaboration with the Harvard Business School
August | MassChallenge Collaboration
HTL provides coaching and clinical guidance to early stage digital start-ups in Massachusetts
October | New Collaboration
The HTL collaboration with MGH TeleHealth and the Cardiology Division for TeleHealth is launched
December | Co.Create Collaboration
HTL experts pair with students to facilitate development of student-led innovation ideas
If you have a project or collaboration opportunity that may be a good fit, contact us with your pitch!