Advances in digital health technologies hold great promise that health care can be delivered in smarter, simpler and more cost effective ways. Mobile technologies can foster patient engagement, enhance care team communication, and improve the health care experience for both patients and their providers. MGH, renowned for delivering the most advanced and highest quality medical care for over two centuries, is well positioned to lead the effort to create and test innovative mobile technologies that enhance and improve care delivery. To this end we are excited to announce the formation and launch of mLab, a collaborative comprised of MGH’s Healthcare Transformation Lab, the Lab of Computer Science, and the MGPO’s Advanced Technology Team. This new collaborative will be led jointly by Eric Isselbacher, MD, Henry Chueh, MD, and David Ting, MD.